Nattokinase (Bac s 1), a subtilisin family serine protease, is a novel allergen contained in the traditional Japanese fermented food natto

Background: Immediate allergy caused by natto, a popular Japanese food prepared by fermenting soybeans with Bacillus subtilis var.natto, has been reported.Polygamma glutamic acid (PGA) in the sticky substance around natto beans Trivets has been reported to be a causative allergen of natto allergy.However, some of our patients with natto allergy wer

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